Dziubla Laboratory

Publications

Peer Reviewed Publications

  1. Cheryl Rabek, T.D. Dziubla and D.A. Puleo*. “The Effect of Plasticizers on the Erosion and Mechanical Properties of Polymeric Films” Journal of Biomaterials Application – (Accepted)
  2. S.P. Authimoolam, D.A. Puleo and T.D. Dziubla*. “Affinity Based Multilayered Polymeric Self-assemblies for Oral Wound Applications.” Advanced Healthcare Materials Epub ahead of Print (2013)
  3. Ramineni SK, Cunningham LL Jr, Dziubla TD, Puleo DA*. “Development of imiquimod-loaded mucoadhesive films for oral dysplasia.” J Pharm Sci. Nov 28. doi: 10.1002/jps.23386 (2012)
  4. Brown ME, Zou Y, Dziubla TD, Puleo DA*. “Effects of composition and setting environment on mechanical properties of a composite bone filler” J Biomed Mater Res A. Sep 10. doi: 10.1002/jbm.a.34399. (2012)
  5. Howard MD, Lu X, Rinehart JJ, Jay M, Dziubla TD*, “Carboxylesterase-triggered hydrolysis of nanoparticle PEGylating agents.” Langmuir. Aug 21;28(33):12030-7 (2012)
  6. J. Ambati, A.M. Lopez, D. Cochran, P. Wattamwar, K. Bean, T.D. Dziubla and S.E. Rankin*, “Loading and Protection of Antioxidant Enzyme on Engineered Silica” Acta Biomaterialia, 8(6):2069-103 PMID:22366223 (2012)
  7. P. P. Wattamwar, D. Biswal, D. B. Cochran, A. Lyvers, Eitel RE, Anderson, KW J. Z. Hilt, and T. D. Dziubla*, “Synthesis and Characterization of Poly(antioxidant β-amino esters) for Controlled Release of Polyphenolic Antioxidants” Acta Biomaterialia, 8(7):2529-37 PMID:22426289 (2012)
  8. D. Biswal, P.P. Wattamwar, T.D. Dziubla, J.Z. Hilt*. “Poly(β-amino ester) hydrogel synthesis by single-step polymerization method.” Polymer 52:5985-5992 (2011)
  9. M. D. Howard, X. Lu, M. Jay, and T. D. Dziubla*, “Optimization of the Lyophilization Process for Long-term Stability of Solid Lipid Nanoparticles” Drug Development and Industrial Pharmacy (2012) EPub Ahead of Print
  10. E. Hood, E. Simone, P.P. Wattamwar, T.D. Dziubla and V.R. Muzykantov, “Nanocarriers for vascular delivery of antioxidants”, Review article, Nanomedicine 6(7):1257-72 (2011)
  11. V.V. Shuvaev, M.A. Ilies, E. Simone, S. Zaitsev, Y. Kim, S. Cai, A. Mahmud ,T. Dziubla ,S. Muro, D.E. Discher, V.R. Muzykantov* “Endothelial Targeting of Antibody-Decorated Polymeric Filomicelles” ACS Nano 27:6991-9 (2011)
  12. P. Wattamwar, S. Hardas, D.A. Butterfield, K. Anderson, T. Dziubla* “Tuning of the Pro-oxidant and Antioxidant Activity of Trolox Through the Controlled Release from Biodegradable Poly(trolox ester) Polymers” J. Biomed Mater Res A 99:184-91 (2011)
  13. Medley JM, Kaplan E, Oz HS, Sundararaj SC, Puleo DA, Dziubla TD*. “Fibrin-targeted block copolymers for the prevention of postsurgical adhesions.” J Biomed Mater Res B Appl Biomater. doi: 10.1002/jbm.b.31876 (2011)
  14. M. Howard, X. Lu, J. Rinehart, M. Jay and T. Dziubla* “Physicochemical Characterization of Nanotemplate Engineered Solid Lipid Nanoparticles” Langmuir 27(5):1964-71 (2011)
  15. J. Kim, M. Howard, T. Dziubla, J. Rinehart, M. Jay and X. Lu* “Uniformity of Drug Payload and its Effect on Stability of Solid Lipid Nanoparticles Containing an Ester Prodrug” ACS Nano (2010)
  16. J. Medley, Heisterberg J, and T Dziubla* “Synthesis and Characterization of CREKA-Targeted Polymers for the Disruption of Fibrin Gel Matrix Propagation.” J Biomater Sci:Poly Ed 22(10):1363-78 (2011)
  17. P. Wattamwar, Y. Mo, R. Wan, R. Palli, Q. Zhang and T. Dziubla*, “Antioxidant Activity of Degradable Polymer Poly(trolox ester) to Suppress Oxidative Stress Injury in the Cells.” Advanced Functional Materials 20:147-154 (2010)
  18. Y Ma, Y Xiong*, J Zhai, H Zhu, and T Dziubla, “Fractionation and Evaluation of Radical Scavenging Peptides from in vitro Digests of Buckwheat Protein.” Food Chemistry 118:582-588 (2010)
  19. J. Medley, E. Beane, E. Kaplan and T Dziubla* “Block copolymers for the rational design of self-forming postsurgical adhesion barriers.” Acta Biomaterialia 6:72-82 (2010)
  20. E Simone*, T Dziubla, D Discher, and V Muzykantov. “Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase.” Biomacromolecules 10:1324-30 (2009)
  21. E Simone*, T. Dziubla, E Arguiri, V Vardon, V Shuvaev, M Christofidou-Solomidou and V Muzykantov. “Loading PEG-catalase into filamentous and spherical polymer nanocarriers” Pharmaceutical Research 26:250-60 (2009)
  22. E. Simone, T.D. Dziubla, and V. R Muzykantov*, “Polymeric Carriers: Role of Geometry in Drug Delivery.” Expert Opinion on Drug Delivery 5:1283-1300 (2008)
  23. M. Howard, M Jay, T. Dziubla, X. Lu*, “PEGylation of Nanocarrier Drug Delivery Systems: State of the Art.” J Biomed Nanotech 4:133-148 (2008)
  24. C. Garnacho, R. Dhami, E. Simone, T. Dziubla, J. Leferovich, E. H. Schuchman, V. Muzykantov, and S. Muro*. “Delivery of acid sphingomyelinase in normal and Niemann-Pick disease mice using ICAM-1-targeted polymer nanoparticles” JPET 325:400-408 (2008)
  25. T.D. Dziubla*, V.V. Shuvaev, N.K. Hong, B. Hawkins, M. Muniswamy, H. Takano, E. Simone, M.T. Nakada, A. Fisher, S.M. Albelda, and V.R. Muzykantov, “Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies.” Biomaterials 2:215-27 (2008)
  26. E. Simone*, T. Dziubla, F. Colon, D. Discher and V.R. Muzykantov. “Amphiphilicity of PEG-PLA diblock copolymer controls the formulation and morphology of nanocarriers protecting loaded therapeutic enzyme from proteolysis” Biomacromolecules 8:3914-21 (2007)
  27. S. Muro*, T.D. Dziubla, W. Qui, J. Leferovich, X. Cui, E. Berk and V.R. Muzykantov  “Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to ICAM-1.” JPET 317(3):1161-9 (2006)
  28. Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR.* “Advanced drug delivery systems that target the vascular endothelium.” Mol Interv. 2:98-112 (2006)
  29. T.D. Dziubla*, A. Karim and V. Muzykantov, “Polymer nanocarriers (PNC) protect loaded catalase cargo from proteolysis.” Journal of Controlled Release 102(2), 427-439, (2005)
  30. T.D. Dziubla and A.M. Lowman*, “Vascularization of PEG-grafted macroporous hydrogel sponges: a 3-dimensional in vitro angiogenesis model utilizing human microvascular endothelial cells.” Journal of Biomedical Materials Research. 68A (4): 603-614, (2004)
  31. T.D. Dziubla, M.C. Torjman, J.I. Joseph, M. Murphy-Tatum and A.M. Lowman*, “Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices.” Biomaterials 22, 2893-2899, (2001)

Conference Proceedings

  1. D. Besser*, G. Swan, T. Dziubla and R. Eitel, “Building Continuous Loop Learning Communities: An Engineering Outreach Case Study” ASEE Southeast Spring Conference Proceedings (2008)
  2. W. Zhang, P. Wattamar, K. Cummins, T. Dziubla, and R. E. Eitel*, “LTCC Based Microfluidic Structures for the Controlled Synthesis of Antioxidant Polymers,” in Proceedings of the IMAPS 2008, 41st International Symposium on Microelectronics. Providence, RI, 2008
  3. A.M. Lowman, T.D. Dziubla and N.A. Peppas*, “Novel networks and gels containing increased amounts of grafted and crosslinked poly(ethylene glycol).” ACS Polymer Prepr., 38(1), (1997)

 

Book Chapters

  1. D. Cochran and T. Dziubla*, “Antioxidant polymers for tuning biomaterial biocompatibility: From Drug Delivery to Tissue Engineering” In: “Antioxidant Polymers Synthesis, Properties, and Applications.” Ed: G. Cirillo, F. Iemma. (2012)
  2. P.P. Wattamwar and T. Dziubla*, “Modulation of the Wound Healing Response Through Oxidation Active Materials” In: Engineering Biomaterials for Regenerative Medicine: Novel Technologies for Clinical Applications.” Ed: S.K. Bhatia. (2012)
  3. J. Medley and T Dziubla*, “Prevention of Postsurgical Adhesions: A Biomaterials Perspective” In: Biological Interactions on Materials Surfaces. Eds: D Puleo and R Bizios. 398-416 (2009)
  4. E. Simone, T. Dziubla, V Shuvaev and V.R. Muzykantov*, “Synthesis and Characterization of Polymer Nanocarriers for Therapeutic Enzyme Delivery.” In: 2nd Edition for Methods in Molecular Biology: Free Radicals and Antioxidant Protocols (In Press)
  5. T.D. Dziubla and V. Muzykantov*, “Nanocarriers for drug delivery to the pulmonary vasculature.” In: Nanoparticulates as Drug Carriers, V Torchilin, Ed. Imperial College Press, London. (2006)
  6. T.D. Dziubla and V. Muzykantov*, “Synthetic carriers for the delivery of protein therapeutics.” In: Biotechnology and Genetic Engineering Reviews Vol. 22., S.E. Harding Ed., Lavoisier Publishing, Paris, France 267-298 (2006)
  7. T. Dziubla*, S. Muro, V. R. Muzykantov and M. Koval, “Nanoscale antioxidant therapeutics.” In: Oxidative Stress, Disease and Cancer, Keshav K. Singh, Ed. Imperial College Press, London. (2006)
  8. A.M. Lowman*, T.D. Dziubla, P. Bures and N.A. Peppas, “Structural and dynamic response of neutral and intelligent networks in biomedical environments.” in N.A. Peppas and M.V. Sefton, eds., “Advances in Chemical Engineering Vol 29: Molecular and Cellular Foundations of Biomaterials.” Academic Press, New York, (2004)
  9. V. Shuvaev, T. Dziubla, R. Wiewrodt and V. Muzykantov*, “Streptavidin-biotin cross-linking of therapeutic enzymes with carrier antibodies: nanoconjugates for protection against endothelial oxidative stress.” In: Methods in Molecular Biology V 283: Bioconjugation Protocols: Strategies and Methods, C.Niemeyer, Ed., Humana Press, (2004)
  10. T.D. Dziubla, M.C. Torjman, J.I. Joseph and A.M. Lowman*, “Implantable drug delivery devices: design of a biomimetic interfacial drug delivery system.” In: Biomimetic Materials and Design: Interactive Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery, A K Dillow and A M Lowman, Eds., Marcel Dekker, (2003)
  11. T.D. Dziubla and A.M. Lowman*, “Smart gels.” In: Encyclopedia of Smart Materials, M. Schwartz  Ed. Wiley and Sons, (2001)